Benjamin Franklin on Vaccinations

In 1736 I lost one of my sons, a fine boy of four years old, by the small-pox, taken in the common way. I long regretted bitterly, and still regret that I had not given it to him by inoculation. This I mention for the sake of parents who omit that operation, on the supposition that they should never forgive themselves if a child died under it; my example showing that the regret may be the same either way, and that, therefore, the safer should be chosen.

 The Story of Inoculation Being Brought to the West

In 1717 Lady Mary travelled to Turkey with her husband, the British Ambassador at Constantinople. There she first witnessed variolation. She described the procedure in a letter to her friend Sarah Chiswell: The small-pox, so fatal, and so general amongst us, is here entirely harmless by the invention of ingrafting, which is the term they give it. There is a set of old women who make it their business perform the operation every autumn... People send to one another to know if any of their f...